Giant porokeratosis of Mibelli with squamous cell carcinoma.

Porokeratosis is a specific disorder of keratinization that has five major clinical types and shows a characteristic cornoid lamella on histopathology. Giant porokeratosis is considered to be a morphological variant of porokeratosis of mibelli. Malignant degeneration has been described in all forms of porokeratosis but highest risk is associated with linear and giant porokeratosis . We report a case of giant porokeratosis with squamous cell carcinomas in 55yr old female patient. To the best of our knowledge this is the largest giant porokeratosis ever reported measuring 62×48cm with two large squamous cell carcinomas.